I have been using the SkyDrive desktop client for a long time now and just recently it stopped working.  When I try some of the advice I've read on these forums, nothing works.  I have made sure Active Scripting is enabled, I have uninstalled and reinstalled...  I even deleted everything on my SkyDrive in case I added a file or folder that was too long or contained illegal characters.  I am running Windows 8 by the way.  As mentioned this has worked for several months up until yesterday.